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Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex

p300, a ubiquitous transcription coactivator, plays an important role in gene activation. Our previous work demonstrated that human inducible nitric oxide synthase (hiNOS) expression can be highly induced with the cytokine mixture (CM) of TNF-α + IL-1β + IFN-γ. In this study, we investigated the fun...

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Veröffentlicht in:PLoS One
Hauptverfasser: Guo, Zhong, Zheng, Liang, Liao, Xinghua, Geller, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713468/
https://ncbi.nlm.nih.gov/pubmed/26751080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146640
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