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Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex

p300, a ubiquitous transcription coactivator, plays an important role in gene activation. Our previous work demonstrated that human inducible nitric oxide synthase (hiNOS) expression can be highly induced with the cytokine mixture (CM) of TNF-α + IL-1β + IFN-γ. In this study, we investigated the fun...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guo, Zhong, Zheng, Liang, Liao, Xinghua, Geller, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713468/
https://ncbi.nlm.nih.gov/pubmed/26751080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146640
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