Mycobacterium leprae-Infected Macrophages Preferentially Primed Regulatory T Cell Responses and Was Associated with Lepromatous Leprosy

BACKGROUND: The persistence of Mycobacterium leprae (M. leprae) infection is largely dependent on the types of host immune responses being induced. Macrophage, a crucial modulator of innate and adaptive immune responses, could be directly infected by M. leprae. We therefore postulated that M. leprae...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Yang, Degang, Shui, Tiejun, Miranda, Jake W., Gilson, Danny J., Song, Zhengyu, Chen, Jia, Shi, Chao, Zhu, Jianyu, Yang, Jun, Jing, Zhichun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713426/
https://ncbi.nlm.nih.gov/pubmed/26751388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004335
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