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Catalytic Self-assembly of DNA Dendritic Complex for Efficient Gene Silencing

A catalytic self-assembled DNA dendritic complex was herein reported and used for siRNA-based gene silencing. This kind of one-pot DNA dendrimer can be conveniently prepared as needed, and it was demonstrated to have better silencing efficiency and lower cytotoxicity than commercial cationic lipid t...

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Lv, Yifan, Peng, Ruizi, Zhou, Yu, Zhang, Xiaobing, Tan, Weihong
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713312/
https://ncbi.nlm.nih.gov/pubmed/26626818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc06937h
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