Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques

Increased chronic immune activation and inflammation are hallmarks of HIV/SIV infection and are highly correlated with progression to AIDS and development of non-AIDS comorbidities, such as hypercoagulability and cardiovascular disease. Intestinal dysfunction resulting in microbial translocation has...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Pandrea, Ivona, Xu, Cuiling, Stock, Jennifer L., Frank, Daniel N., Ma, Dongzhu, Policicchio, Benjamin B., He, Tianyu, Kristoff, Jan, Cornell, Elaine, Haret-Richter, George S., Trichel, Anita, Ribeiro, Ruy M., Tracy, Russell, Wilson, Cara, Landay, Alan L., Apetrei, Cristian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713071/
https://ncbi.nlm.nih.gov/pubmed/26764484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005384
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