Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology

Tumor necrosis factor (TNF) is critical for controlling many intracellular infections, but can also contribute to inflammation. It can promote the destruction of important cell populations and trigger dramatic tissue remodeling following establishment of chronic disease. Therefore, a better understa...

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Publicado en:PLoS Pathog
Autores principales: Montes de Oca, Marcela, Kumar, Rajiv, de Labastida Rivera, Fabian, Amante, Fiona H, Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Muller, Werner, Cretney, Erika, Nutt, Stephen L., Smyth, Mark J., Haque, Ashraful, Hill, Geoffrey R., Sundar, Shyam, Kallies, Axel, Engwerda, Christian R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713066/
https://ncbi.nlm.nih.gov/pubmed/26765224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005398
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