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Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology

Tumor necrosis factor (TNF) is critical for controlling many intracellular infections, but can also contribute to inflammation. It can promote the destruction of important cell populations and trigger dramatic tissue remodeling following establishment of chronic disease. Therefore, a better understa...

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Pubblicato in:PLoS Pathog
Autori principali: Montes de Oca, Marcela, Kumar, Rajiv, de Labastida Rivera, Fabian, Amante, Fiona H, Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Muller, Werner, Cretney, Erika, Nutt, Stephen L., Smyth, Mark J., Haque, Ashraful, Hill, Geoffrey R., Sundar, Shyam, Kallies, Axel, Engwerda, Christian R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713066/
https://ncbi.nlm.nih.gov/pubmed/26765224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005398
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