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Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration

Postnatal tissue quiescence is thought to be a default state in the absence of a proliferative stimulus such as injury. Previous studies have demonstrated that certain embryonic development programs are reactivated aberrantly in adult organs to drive repair and regeneration(1–3), it is not well unde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Peng, Tien, Frank, David B., Kadzik, Rachel S., Morley, Michael P., Rathi, Komal S., Wang, Tao, Zhou, Su, Cheng, Lan, Lu, Min Min, Morrisey, Edward E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713039/
https://ncbi.nlm.nih.gov/pubmed/26436454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14984
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