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Patients harboring EGFR mutation after primary resistance to crizotinib and response to EGFR-tyrosine kinase inhibitor

Anaplastic lymphoma kinase (ALK) rearrangement lung cancer responds to ALK tyrosine kinase inhibitors. It is known that many cases ultimately acquired resistance to crizotinib. However, a case of primary resistance is rare. We present a case of harboring exon 19 deletion in epidermal growth factor r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Wang, Wenxian, Jiang, Xiaowen, Song, Zhengbo, Zhang, Yiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712969/
https://ncbi.nlm.nih.gov/pubmed/26811689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S97100
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