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Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish

Congenital heart disease often features structural abnormalities that emerge during development. Accumulating evidence indicates a crucial role for cardiac contraction and the resulting fluid forces in shaping the heart, yet the molecular basis of this function is largely unknown. Using the zebrafis...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Samsa, Leigh Ann, Givens, Chris, Tzima, Eleni, Stainier, Didier Y. R., Qian, Li, Liu, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712836/
https://ncbi.nlm.nih.gov/pubmed/26628092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.125724
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