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Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1

Changes in cell morphology require coordination of plasma membrane turnover and cytoskeleton dynamics, processes that are regulated by Rho GTPases. Here, we describe how a direct interaction between the Rho GTPase Cdc42 and the GTPase-activating protein (GAP) GRAF1 (also known as ARHGAP26), facilita...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Francis, Monika K., Holst, Mikkel R., Vidal-Quadras, Maite, Henriksson, Sara, Santarella-Mellwig, Rachel, Sandblad, Linda, Lundmark, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712783/
https://ncbi.nlm.nih.gov/pubmed/26446261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.174417
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