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Sry-Independent Overexpression of Sox9 Supports Spermatogenesis and Fertility in the Mouse

The Y chromosome gene Sry is responsible for sex determination in mammals and initiates a cascade of events that direct differentiation of bipotential genital ridges toward male-specific fate. Sox9 is an autosomal gene and a primary downstream target of SRY. The activation of Sox9 in the absence of...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Principais autores: Ortega, Egle A., Ruthig, Victor A., Ward, Monika A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712697/
https://ncbi.nlm.nih.gov/pubmed/26536904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.135400
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