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Sequencing of lariat termini in S. cerevisiae reveals 5′ splice sites, branch points, and novel splicing events

Pre-mRNA splicing is a central step in the shaping of the eukaryotic transcriptome and in the regulation of gene expression. Yet, due to a focus on fully processed mRNA, common approaches for defining pre-mRNA splicing genome-wide are suboptimal—especially with respect to defining the branch point s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA
Egile Nagusiak: Qin, Daoming, Huang, Lei, Wlodaver, Alissa, Andrade, Jorge, Staley, Jonathan P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712674/
https://ncbi.nlm.nih.gov/pubmed/26647463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052829.115
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