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Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

There is an urgent need to develop molecular biomarkers of brain age in order to advance our understanding of age related neurodegeneration. Recently, we developed a highly accurate epigenetic biomarker of tissue age (known as epigenetic clock) which is based on DNA methylation levels. Here we use n...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Levine, Morgan E., Lu, Ake T., Bennett, David A., Horvath, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712342/
https://ncbi.nlm.nih.gov/pubmed/26684672
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