Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study

PURPOSE: Age induces a progressive decline in functional reserve and impacts cancer treatments. Telomere attrition leads to tissue senescence. We tested the hypothesis that telomere length (TL) could predict patient vulnerability and outcome with cancer treatment. PATIENTS AND METHODS: An ancillary...

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Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Falandry, Claire, Horard, Béatrice, Bruyas, Amandine, Legouffe, Eric, Cretin, Jacques, Meunier, Jérôme, Alexandre, Jérôme, Delecroix, Valérie, Fabbro, Michel, Certain, Marie-Noëlle, Maraval-Gaget, Raymonde, Pujade-Lauraine, Eric, Gilson, Eric, Freyer, Gilles
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712332/
https://ncbi.nlm.nih.gov/pubmed/26638179
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