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The PTEN tumor suppressor gene and its role in lymphoma pathogenesis

The phosphatase and tensin homolog gene PTEN is one of the most frequently mutated tumor suppressor genes in human cancer. Loss of PTEN function occurs in a variety of human cancers via its mutation, deletion, transcriptional silencing, or protein instability. PTEN deficiency in cancer has been asso...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Wang, Xiaoxiao, Huang, Huiqiang, Young, Ken H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712330/
https://ncbi.nlm.nih.gov/pubmed/26655726
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