Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased β1,6-N-Glycosylation and Increased Susceptibility to Galectin-3 Binding

Epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells is a crucial event in the onset of proliferative vitreoretinopathy (PVR), the most common reason for treatment failure in retinal detachment surgery. We studied alterations in the cell surface glycan expression profile up...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Priglinger, Claudia S., Obermann, Jara, Szober, Christoph M., Merl-Pham, Juliane, Ohmayer, Uli, Behler, Jennifer, Gruhn, Fabian, Kreutzer, Thomas C., Wertheimer, Christian, Geerlof, Arie, Priglinger, Siegfried G., Hauck, Stefanie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712018/
https://ncbi.nlm.nih.gov/pubmed/26760037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146887
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