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Deletion of Lysophosphatidic Acid Receptor 3 (Lpar3) Disrupts Fine Local Balance of Progesterone and Estrogen Signaling in Mouse Uterus During Implantation

Lpar3 encodes LPA(3), the third G protein-coupled receptor for lysophosphatidic acid (LPA). Lpar3(−/−) female mice had delayed embryo implantation. Their serum progesterone and estrogen levels were comparable with control on Gestation Day 3.5 (D3.5) at 1100 h. There was reduced cell proliferation in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Diao, Honglu, Li, Rong, El Zowalaty, Ahmed E., Xiao, Shuo, Zhao, Fei, Dudley, Elizabeth A., Ye, Xiaoqin
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712008/
https://ncbi.nlm.nih.gov/pubmed/26447143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.131110
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