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Steroidogenic Factor 1 Differentially Regulates Fetal and Adult Leydig Cell Development in Male Mice
The nuclear receptor steroidogenic factor 1 (SF-1, AD4BP, NR5A1) is a key regulator of the endocrine axes and is essential for adrenal and gonad development. Partial rescue of Nr5a1(−/−) mice with an SF-1-expressing transgene caused a hypomorphic phenotype that revealed its roles in Leydig cell deve...
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| Publicat a: | Biol Reprod |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for the Study of Reproduction, Inc.
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711904/ https://ncbi.nlm.nih.gov/pubmed/26269506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.131193 |
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