Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs

Population bottlenecks, inbreeding, and artificial selection can all, in principle, influence levels of deleterious genetic variation. However, the relative importance of each of these effects on genome-wide patterns of deleterious variation remains controversial. Domestic and wild canids offer a po...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Marsden, Clare D., Ortega-Del Vecchyo, Diego, O’Brien, Dennis P., Taylor, Jeremy F., Ramirez, Oscar, Vilà, Carles, Marques-Bonet, Tomas, Schnabel, Robert D., Wayne, Robert K., Lohmueller, Kirk E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711855/
https://ncbi.nlm.nih.gov/pubmed/26699508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512501113
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