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Effects of aging on circadian patterns of gene expression in the human prefrontal cortex

With aging, significant changes in circadian rhythms occur, including a shift in phase toward a “morning” chronotype and a loss of rhythmicity in circulating hormones. However, the effects of aging on molecular rhythms in the human brain have remained elusive. Here, we used a previously described ti...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Chen, Cho-Yi, Logan, Ryan W., Ma, Tianzhou, Lewis, David A., Tseng, George C., Sibille, Etienne, McClung, Colleen A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711850/
https://ncbi.nlm.nih.gov/pubmed/26699485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508249112
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