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Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

Complement receptor 2 (CR2/CD21) is predominantly expressed on the surface of mature B cells where it forms part of a coreceptor complex that functions, in part, to modulate B-cell receptor signal strength. CR2/CD21 expression is tightly regulated throughout B-cell development such that CR2/CD21 can...

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Publicado en:Cell Mol Immunol
Autores principales: Taylor, Rhonda L, Cruickshank, Mark N, Karimi, Mahdad, Ng, Han Leng, Quail, Elizabeth, Kaufman, Kenneth M, Harley, John B, Abraham, Lawrence J, Tsao, Betty P, Boackle, Susan A, Ulgiati, Daniela
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711682/
https://ncbi.nlm.nih.gov/pubmed/25640655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.138
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