Complement 5a receptor-mediated neutrophil dysfunction is associated with a poor outcome in sepsis

Complement 5a (C5a) has been implicated in the pathogenesis of sepsis by inducing the functional impairment of neutrophils; however, the utility of C5a receptors (C5aRs; C5aR and C5L2) as biomarkers for the management of sepsis is uncertain. This study investigated the dynamic expression of C5aR and...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Xu, Ruonan, Lin, Fang, Bao, Chunmei, Huang, Huihuang, Ji, Chengcheng, Wang, Siyu, Jin, Lei, Sun, Lijian, Li, Ke, Zhang, Zheng, Wang, Fu-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711680/
https://ncbi.nlm.nih.gov/pubmed/25726869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.136
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