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Celastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition

Celastrol, also named as tripterine, is a pharmacologically active ingredient extracted from the root of traditional Chinese herb Tripterygium wilfordii Hook F with potent anti-inflammatory and anti-tumor activities. In the present study, we investigated the effects of celastrol on ulcerative coliti...

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Publicado en:Front Pharmacol
Autores principales: Lin, Lianjie, Sun, Yan, Wang, Dongxu, Zheng, Shihang, Zhang, Jing, Zheng, Changqing
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711309/
https://ncbi.nlm.nih.gov/pubmed/26793111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00320
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