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Nitric oxide activates cyclooxygenase enzymes.

We have evaluated the role of nitric oxide (NO) on the activity of the constitutive and induced forms of cyclooxygenase (COX; COX-1 and COX-2, respectively). Induction of NO synthase (NOS) and COX (COX-2) in the mouse macrophage cell line RAW264.7 by Escherichia coli lipopolysaccharide (1 microgram/...

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Autors principals: Salvemini, D, Misko, T P, Masferrer, J L, Seibert, K, Currie, M G, Needleman, P
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC47112/
https://ncbi.nlm.nih.gov/pubmed/7688473
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