Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial

BACKGROUND: Current artesunate (ARS) regimens for severe malaria are complex. Once daily intramuscular (i.m.) injection for 3 d would be simpler and more appropriate for remote health facilities than the current WHO-recommended regimen of five intravenous (i.v.) or i.m. injections over 4 d. We compa...

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Vydáno v:PLoS Med
Hlavní autoři: Kremsner, Peter G., Adegnika, Akim A., Hounkpatin, Aurore B., Zinsou, Jeannot F., Taylor, Terrie E., Chimalizeni, Yamikani, Liomba, Alice, Kombila, Maryvonne, Bouyou-Akotet, Marielle K., Mawili Mboumba, Denise P., Agbenyega, Tsiri, Ansong, Daniel, Sylverken, Justice, Ogutu, Bernhards R., Otieno, Godfrey A., Wangwe, Anne, Bojang, Kalifa A., Okomo, Uduak, Sanya-Isijola, Frank, Newton, Charles R., Njuguna, Patricia, Kazungu, Michael, Kerb, Reinhold, Geditz, Mirjam, Schwab, Matthias, Velavan, Thirumalaisamy P., Nguetse, Christian, Köhler, Carsten, Issifou, Saadou, Bolte, Stefanie, Engleitner, Thomas, Mordmüller, Benjamin, Krishna, Sanjeev
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710539/
https://ncbi.nlm.nih.gov/pubmed/26757276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001938
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