Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis

B cells are involved in driving relapsing-remitting multiple sclerosis (RRMS), as demonstrated by the positive effect of therapeutic B-cell depletion. Aside from producing antibodies, B cells are efficient antigen-presenting and cytokine-secreting cells. Diverse polyclonal stimuli have been used to...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Nielsen, Claus H., Börnsen, Lars, Sellebjerg, Finn, Brimnes, Marie K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710535/
https://ncbi.nlm.nih.gov/pubmed/26756931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146971
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