CRTAM determines the CD4(+) cytotoxic T lymphocyte lineage

Naive T cells differentiate into various effector T cells, including CD4(+) helper T cell subsets and CD8(+) cytotoxic T cells (CTL). Although cytotoxic CD4(+) T cells (CD4(+)CTL) also develop from naive T cells, the mechanism of development is elusive. We found that a small fraction of CD4(+) T cel...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Takeuchi, Arata, Badr, Mohamed El Sherif Gadelhaq, Miyauchi, Kosuke, Ishihara, Chitose, Onishi, Reiko, Guo, Zijin, Sasaki, Yoshiteru, Ike, Hiroshi, Takumi, Akiko, Tsuji, Noriko M., Murakami, Yoshinori, Katakai, Tomoya, Kubo, Masato, Saito, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710199/
https://ncbi.nlm.nih.gov/pubmed/26694968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150519
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