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Balance and Imbalance in the Immune System: Life on the Edge
CTLA-4 is a key immune checkpoint in maintaining self-tolerance, which can be co-opted by cancer to evade immune attack. In Science, Kuehn et al. (2014) describe clinical manifestations from inherited heterozygous CTLA4 mutations, and some are reminiscent of immune-related consequences from anti-CTL...
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| Publicado no: | Immunity |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710093/ https://ncbi.nlm.nih.gov/pubmed/25517610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.11.005 |
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