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Renin gene rs1464816 polymorphism contributes to chronic kidney disease progression in ADPKD

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disorder and is a common genetic cause of chronic renal failure in children and adults. The enzyme renin plays a key role in the RAAS cascade and an important role in the development of hypertension and progression of re...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Ramanathan, Gnanasambandan, Elumalai, Ramprasad, Periyasamy, Soundararajan, Lakkakula, Bhaskar V. K. S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710007/
https://ncbi.nlm.nih.gov/pubmed/26753721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0217-0
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