RASSF1 tumor suppressor gene in pancreatic ductal adenocarcinoma: correlation of expression, chromosomal status and epigenetic changes

BACKGROUND: The Ras Association Domain Family Member 1 (RASSF1) is one of the most frequently reported methylation-inactivated tumor suppressor genes in primary pancreatic ductal adenocarcinomas (PDAC). Limited information is still available about the impact of RASSF1 gene silencing on the expressio...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Amato, Eliana, Barbi, Stefano, Fassan, Matteo, Luchini, Claudio, Vicentini, Caterina, Brunelli, Matteo, Malleo, Giuseppe, Scarpa, Aldo, Malpeli, Giorgio
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710004/
https://ncbi.nlm.nih.gov/pubmed/26754001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2048-0
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