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MicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical use

In the past two decades, microRNAs have emerged as crucial mediators of organ development and human disease. Here, we discuss their role as drivers or suppressors of the hallmarks of cancer during tumorigenesis and progression, in defining interpatient heterogeneity and the promise of therapeutic ap...

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Veröffentlicht in:Genome Biol
Hauptverfasser: Nana-Sinkam, S Patrick, Croce, Carlo M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709998/
https://ncbi.nlm.nih.gov/pubmed/25315999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0445-8
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