Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells

BACKGROUND: Cycloartane triterpenoids exhibited anticancer effects. This study aims to identify any potential novel anticancer cycloartane triterpenoids from Cimicifuga foetida L. rhizome (Sheng ma) and the mode of actions. METHODS: Cycloartane triterpenoids were isolated from the C. foetida rhizome...

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Gepubliceerd in:Chin Med
Hoofdauteurs: Sun, Hai-yan, Liu, Bei-bei, Hu, Jian-yang, Xu, Li-jia, Chan, Shun-wan, Chan, Chi-on, Mok, Daniel K. W., Zhang, Dong-mei, Ye, Wen-cai, Chen, Si-bao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709995/
https://ncbi.nlm.nih.gov/pubmed/26759603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-015-0073-6
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