TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described. In this study, both in vitro (HPCs cocultured with hepatic stellate cells (HSCs)...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Yang, Ai-Ting, Hu, Dou-Dou, Wang, Ping, Cong, Min, Liu, Tian-Hui, Zhang, Dong, Sun, Ya-Meng, Zhao, Wen-Shan, Jia, Ji-Dong, You, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709730/
https://ncbi.nlm.nih.gov/pubmed/26839553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1492694
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