Downregulation of Heparanase Expression Results in Suppression of Invasion, Migration, and Adhesion Abilities of Hepatocellular Carcinoma Cells

Objective. Heparanase (HPSE) is high-expressed in most malignant tumors including hepatocellular carcinoma (HCC) and promotes cancer cell invasion and migration. The aim of the study is to explore whether HPSE enhances adhesion in metastasis of HCC cells. Methods. HPSE expressions in human HCC cells...

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Vydáno v:Biomed Res Int
Hlavní autoři: Chen, Xiao-Peng, Luo, Jun-Sheng, Tian, Ye, Nie, Chen-Lin, Cui, Wei, Zhang, Wei-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709605/
https://ncbi.nlm.nih.gov/pubmed/26839882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/241983
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