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Niche Appropriation by Drosophila Intestinal Stem Cell Tumors
Mutations that inhibit differentiation in stem cell lineages are a common early step in cancer development, but precisely how a loss of differentiation initiates tumorigenesis is unclear. We investigated Drosophila intestinal stem cell (ISC) tumors generated by suppressing Notch (N) signaling, which...
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| Опубликовано в: : | Nat Cell Biol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4709566/ https://ncbi.nlm.nih.gov/pubmed/26237646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3214 |
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