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Altered Expression of Endoplasmic Reticulum Stress Associated Genes in Hippocampus of Learned Helpless Rats: Relevance to Depression Pathophysiology

The unfolded protein response (UPR) is an evolutionarily conserved defensive mechanism that is used by cells to correct misfolded proteins that accumulate in the endoplasmic reticulum. These proteins are misfolded as a result of physical stress on a cell and initiate a host of downstream effects tha...

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書目詳細資料
發表在:Front Pharmacol
Main Authors: Timberlake, Matthew A., Dwivedi, Yogesh
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709448/
https://ncbi.nlm.nih.gov/pubmed/26793110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00319
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