Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines

MTAP is a ubiquitously expressed gene important for adenine and methionine salvage. The gene is located at 9p21, a chromosome region often deleted in breast carcinomas, similar to CDKN2A, a recognized tumor suppressor gene. Several research groups have shown that MTAP acts as a tumor suppressor, and...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: de Oliveira, Sarah Franco Vieira, Ganzinelli, Monica, Chilà, Rosaria, Serino, Leandro, Maciel, Marcos Euzébio, Urban, Cícero de Andrade, de Lima, Rubens Silveira, Cavalli, Iglenir João, Generali, Daniele, Broggini, Massimo, Damia, Giovanna, Ribeiro, Enilze Maria de Souza Fonseca
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709099/
https://ncbi.nlm.nih.gov/pubmed/26751376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145647
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