Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde

Cinnamomum verum is used to make the spice cinnamon and has been used as a traditional Chinese herbal medicine for various applications. We evaluated the anticancer effect of 2-methoxycinnamaldehyde (2-MCA), a constituent of the bark of the plant, and its underlying molecular biomarkers associated w...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Perng, Daw-Shyong, Tsai, Yu-Hsin, Cherng, Jonathan, Wang, Jeng-Shing, Chou, Kuo-Shen, Shih, Chia-Wen, Cherng, Jaw-Ming
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708962/
https://ncbi.nlm.nih.gov/pubmed/26792981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93599
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