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Tailored Assays for Pharmacokinetic and Pharmacodynamic Investigations of Aliskiren and Enalapril in Children: An Application in Serum, Urine, and Saliva

OBJECTIVES: Drugs that are effectively used to treat hypertension in adults (e.g., enalapril) have not been sufficiently investigated in children. Studies required for pediatric approval require special consideration regarding ethics, study design, and conduct and are also associated with special de...

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Detalhes bibliográficos
Publicado no:J Pediatr Pharmacol Ther
Main Authors: Burckhardt, Bjoern B., Tins, Jutta, Ramusovic, Sergej, Läer, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708953/
https://ncbi.nlm.nih.gov/pubmed/26766933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-20.6.431
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