Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination

OBJECTIVE: We aimed to examine the regulation of lipocalin-2 (LCN2) in multiple sclerosis (MS) and its potential functional relevance with regard to myelination and neurodegeneration. METHODS: We determined LCN2 levels in 3 different studies: (1) in CSF and plasma from a case-control study comparing...

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Pubblicato in:Neurol Neuroimmunol Neuroinflamm
Autori principali: Al Nimer, Faiez, Elliott, Christina, Bergman, Joakim, Khademi, Mohsen, Dring, Ann M., Aeinehband, Shahin, Bergenheim, Tommy, Romme Christensen, Jeppe, Sellebjerg, Finn, Svenningsson, Anders, Linington, Christopher, Olsson, Tomas, Piehl, Fredrik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708925/
https://ncbi.nlm.nih.gov/pubmed/26770997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000191
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