An erythromycin analog produced by reprogramming of polyketide synthesis.

The polyketide-derived macrolactone of the antibiotic erythromycin is made through successive condensation and processing of seven three-carbon units. The fourth cycle involves complete processing of the newly formed beta-keto group (beta-keto reduction, dehydration, and enoyl reduction) to yield th...

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Donadio, S, McAlpine, J B, Sheldon, P J, Jackson, M, Katz, L
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1993
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8346223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7119
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!