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The RET G691S polymorphism is a germline variant in desmoplastic malignant melanoma
The RET protooncogene was originally identified in 1985. It encodes for a receptor tyrosine kinase. The RET receptor is activated by its ligand glial cell-derived neurotrophic factor. A polymorphism, RETp (G691S), in the intracellular juxtamembrane domain of RET, which enhances signaling by glial ce...
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| Publicado no: | Melanoma Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4708080/ https://ncbi.nlm.nih.gov/pubmed/22189301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0b013e32834defd6 |
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