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Evaluating the use of HILIC in large-scale, multi dimensional proteomics: Horses for courses?

Despite many recent advances in instrumentation, the sheer complexity of biological samples remains a major challenge in large-scale proteomics experiments, reflecting both the large number of protein isoforms and the wide dynamic range of their expression levels. However, while the dynamic range of...

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Pubblicato in:Int J Mass Spectrom
Autori principali: Bensaddek, Dalila, Nicolas, Armel, Lamond, Angus I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708065/
https://ncbi.nlm.nih.gov/pubmed/26869852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2015.07.029
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