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Structure of methionine γ-lyase from Clostridium sporogenes

Methionine γ-lyase (MGL) is a pyridoxal 5′-phosphate-dependent enzyme that catalyzes the γ-elimination reaction of l-methionine. The enzyme is a promising target for therapeutic intervention in some anaerobic pathogens and has attracted interest as a potential cancer treatment. The crystal structure...

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Détails bibliographiques
Publié dans:Acta Crystallogr F Struct Biol Commun
Auteurs principaux: Revtovich, Svetlana, Anufrieva, Natalya, Morozova, Elena, Kulikova, Vitalia, Nikulin, Alexey, Demidkina, Tatyana
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708053/
https://ncbi.nlm.nih.gov/pubmed/26750487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15023869
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