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DNA prime-protein boost based vaccination with a conserved region of leptospiral immunoglobulin-like A and B proteins enhances protection against leptospirosis
Leptospirosis is a zoonotic disease caused by pathogenic spirochetes of theLeptospira genus. Vaccination with bacterins has severe limitations. Here, we evaluated the N-terminal region of the leptospiral immunoglobulin-like B protein (LigBrep) as a vaccine candidate against leptospirosis using immun...
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| Publicado no: | Mem Inst Oswaldo Cruz |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Instituto Oswaldo Cruz, Ministério da Saúde
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4708018/ https://ncbi.nlm.nih.gov/pubmed/26676320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760150222 |
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