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EP400 Deposits H3.3 into Promoters and Enhancers During Gene Activation

Gene activation in metazoans is accompanied by the presence of histone variants H2AZ and H3.3 within promoters and enhancers. It is not known however what protein deposits H3.3 into chromatin or whether variant chromatin plays a direct role in gene activation. Here we show that chromatin containing...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Pradhan, Suman K., Su, Trent, Yen, Linda, Jacquet, Karine, Huang, Chengyang, Cote, Jacques, Kurdistani, Siavash K., Carey, Michael F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707986/
https://ncbi.nlm.nih.gov/pubmed/26669263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.10.039
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