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Protein-RNA networks revealed through covalent RNA marks

Protein-RNA networks are ubiquitous and central in biological control. We present an approach, termed “RNA Tagging,” that identifies protein-RNA interactions in vivo by analyzing purified cellular RNA, without protein purification or crosslinking. An RNA-binding protein of interest is fused to an en...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Lapointe, Christopher P., Wilinski, Daniel, Saunders, Harriet A. J., Wickens, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707952/
https://ncbi.nlm.nih.gov/pubmed/26524240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3651
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