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Telomere Length in Epidemiology: A Biomarker of Aging, Age-Related Disease, Both, or Neither?
Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during mitosis. Short telomeres induce cellular senescence. As an indicator of oxidative stress and senescence (2 processes thought to...
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| Publicado no: | Epidemiol Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707879/ https://ncbi.nlm.nih.gov/pubmed/23302541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/epirev/mxs008 |
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