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Telomere Length in Epidemiology: A Biomarker of Aging, Age-Related Disease, Both, or Neither?

Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during mitosis. Short telomeres induce cellular senescence. As an indicator of oxidative stress and senescence (2 processes thought to...

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Dades bibliogràfiques
Publicat a:Epidemiol Rev
Autors principals: Sanders, Jason L., Newman, Anne B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707879/
https://ncbi.nlm.nih.gov/pubmed/23302541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/epirev/mxs008
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