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Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice
BACKGROUND: Myocardial fibrosis is an essential hallmark of diabetic cardiomyopathy (DCM) contributing to cardiac dysfunctions. Resveratrol, an antioxidant, exerts its anti-fibrotic effect via inhibition of oxidative stress, while the underlying molecular mechanism remains largely elusive. Periostin...
שמור ב:
הוצא לאור ב: | BMC Cardiovasc Disord |
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Main Authors: | , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
BioMed Central
2016
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707778/ https://ncbi.nlm.nih.gov/pubmed/26750922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-015-0169-z |
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