A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis

[Image: see text] Antifolates are widely used to treat several diseases but are not currently used in the first-line treatment of tuberculosis, despite evidence that some of these molecules can target Mycobacterium tuberculosis (Mtb) bacilli in vitro. To identify new antifolate candidates for animal...

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Bibliographic Details
Published in:ACS Infect Dis
Main Authors: Kumar, Anuradha, Guardia, Ana, Colmenarejo, Gonzalo, Pérez, Esther, Gonzalez, Ruben R., Torres, Pedro, Calvo, David, Gómez, Ruben M., Ortega, Fátima, Jiménez, Elena, Gabarro, Raquel C., Rullás, Joaquín, Ballell, Lluis, Sherman, David R.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707675/
https://ncbi.nlm.nih.gov/pubmed/26771003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00063
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