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Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes

Imaging lipid organization in cell membranes requires advanced fluorescent probes. Here, we show that a recently synthesized push-pull pyrene (PA), similarly to popular probe Laurdan, changes the emission maximum as a function of lipid order, but outperforms it by spectroscopic properties. In additi...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Niko, Yosuke, Didier, Pascal, Mely, Yves, Konishi, Gen-ichi, Klymchenko, Andrey S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707542/
https://ncbi.nlm.nih.gov/pubmed/26750324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18870
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